Improve pigmentation and scarring
Treatment
Polynucleotides

Treatment at a glance
Key benefit
Treatment time
15-30 minutes
Pain
Mild
Longevity
6-12 months
Price
From £300
Key benefit
Improve pigmentation and scarring
Treatment time
15-30 minutes
Pain
Mild
Longevity
6-12 months
Price
From £300
London’s Leading Doctor-Led Polynucleotide Clinic
Polynucleotides redefine regenerative skin therapy. These advanced, bio-stimulating injections activate your skin’s own renewal processes, restoring hydration, boosting elasticity, and strengthening cellular structure.
Trusted by over 10,000 patients across London.
What are Polynucleotides?
Polynucleotides are highly purified molecules derived from salmon DNA, carefully selected for their compatibility with human skin.
These advanced bio-regenerators work beneath the surface to revive and strengthen your skin in three key ways:
- Boost collagen and elastin by stimulating fibroblasts, resulting in firmer, more resilient skin.
- Deeply hydrate by drawing water into the skin, enhancing elasticity and overall tone.
- Defend against inflammation and oxidative stress, supporting a clearer, healthier complexion.
Are Polynucleotides For You?
You’re a good candidate for polynucleotides if you want to:
- Smooth fine lines and wrinkles by boosting collagen and elastin
- Hydrate and improve dehydrated, dull skin
- Even out pigmentation and uneven tone
- Refresh tired areas like dark circles or minimise scarring
This suits anyone seeking natural, lasting rejuvenation that repairs skin at a deeper level rather than just hydrating the surface.
Before & Afters
Subtle refinement achieved through precision, proportion, and restraint. At Dr Hass Clinic, no two results are ever the same.
Benefits of Polynucleotide Injections
Polynucleotide injections provide a range of benefits, including:
- Skin Rejuvenation: Improves skin texture, firmness, and hydration levels.
- Anti-Ageing: Reduces fine lines and wrinkles by boosting collagen and elastin production.
- Skin Repair: Accelerates healing and regeneration, particularly after skin damage or aesthetic treatments.
- Natural Results: Enhances your natural beauty without altering facial expressions.
- Safe and Biocompatible: Well-tolerated and suitable for most skin types.
Accreditations & Professional Memberships
Polynucleotides for Under-Eye Rejuvenation
The under-eye area is thin and delicate, making it one of the first places to show fine lines, crepiness, and hollowing. Polynucleotides work differently to traditional fillers here:
- They regenerate rather than volumise. Tear trough filler adds volume to smooth hollowing, while polynucleotides stimulate collagen and elastin to improve the skin itself.
- They hydrate thin skin, improving elasticity and softening crepey texture.
- They soften dark circles by supporting microcirculation, without adding bulk to the area.
- They can be combined with tear trough filler for patients dealing with both hollowing and poor skin quality.
Read more about polynucleotides for under-eye rejuvenation →
Why Choose Dr Hass Clinic?
Trust your results to expert medical care at Dr Hass Clinic, where every treatment combines clinical precision with aesthetic artistry for natural, refined outcomes.
- All procedures are performed by Dr Hasaneen Al Janabi, a GMC-registered aesthetics doctor and Royal College of Surgeons member, who has treated over 10,000 patients with exceptional results.
- Each treatment is 100% personalised to your skin’s unique needs, using premium, clinically proven products for lasting, natural rejuvenation.
- You will receive comprehensive care from consultation to aftercare and follow-up, ensuring optimal safety, comfort, and confidence.
- Our Mayfair clinic provides a luxurious, discreet setting designed for your comfort and peace of mind.
FAQs
How do polynucleotide injections improve skin elasticity?
Polynucleotides stimulate fibroblasts, the cells responsible for producing collagen and elastin. These are key proteins that maintain skin’s firmness and elasticity. This boost helps tighten and strengthen the skin, reducing sagging and giving a more lifted, youthful appearance.
What areas can be treated with polynucleotides?
Common treatment areas include the under-eyes, cheeks, neck, décolletage, hands, arms, and even the scalp for improving hair and skin health.
Are polynucleotide injections safe?
Yes, they are highly biocompatible and safe for most individuals. Our team at Dr Hass Clinic ensures the highest standards of safety and care during every treatment.
Are polynucleotide injections suitable for sensitive skin?
Yes, they are highly biocompatible and safe for most individuals. Our team at Dr Hass Clinic ensures the highest standards of safety and care during every treatment.
How many treatments are usually needed?
Typically, an initial course of 1 to 3 sessions is recommended, spaced about 2 to 4 weeks apart. Maintenance sessions are encouraged every 8 to 12 months.
How soon will I see results?
Results typically become noticeable within 1-2 weeks after treatment, as the skin begins to repair and rejuvenate itself. Improvements will continue over the following weeks as collagen production increases.
How long do the results last?
The effects can last up to six months or more, depending on your skin type, lifestyle, and the number of sessions completed. Periodic maintenance treatments are recommended for optimal, long-lasting results.
Is the treatment painful?
The injections are generally well-tolerated by patients. A topical numbing cream can be applied before the procedure to minimise any discomfort during the treatment.
Is there downtime after polynucleotide treatment?
Most patients resume normal activities immediately after treatment. Minor redness or swelling may occur but typically resolves within a few days.
What should I avoid after the treatment?
After your treatment, it is recommended to avoid intense exercise, saunas, and direct sun exposure for at least 24-48 hours to ensure optimal results and reduce the risk of irritation.
How do polynucleotide injections differ from other skin rejuvenation treatments?
Unlike hyaluronic acid-based fillers, which primarily add volume, polynucleotide injections focus on repairing and regenerating the skin at a cellular level. They provide long-lasting improvements in skin quality, hydration, and elasticity rather than temporary volumising effects.
Don’t Take Our Word For it…
Our clients’ satisfaction is at the heart of everything we do. We take immense pride in helping individuals enhance their natural beauty and boost their confidence.