Treatment

Polynucleotides

Polynucleotides Treatment Stage Image - Dr Hass ClinicPolynucleotides Treatment Stage Image - Dr Hass Clinic

Treatment at a glance

Key benefit

Improve pigmentation and scarring

Treatment time

15-30 minutes

Pain

Mild

Longevity

6-12 months

Price

From £300

London’s Leading Doctor-Led Polynucleotide Clinic

Polynucleotides redefine regenerative skin therapy. These advanced, bio-stimulating injections activate your skin’s own renewal processes, restoring hydration, boosting elasticity, and strengthening cellular structure.

Trusted by over 10,000 patients across London.

What are Polynucleotides?

Polynucleotides are highly purified molecules derived from salmon DNA, carefully selected for their compatibility with human skin.

These advanced bio-regenerators work beneath the surface to revive and strengthen your skin in three key ways:

  • Boost collagen and elastin by stimulating fibroblasts, resulting in firmer, more resilient skin.
  • Deeply hydrate by drawing water into the skin, enhancing elasticity and overall tone.
  • Defend against inflammation and oxidative stress, supporting a clearer, healthier complexion.

Are Polynucleotides For You?

You’re a good candidate for polynucleotides if you want to:

This suits anyone seeking natural, lasting rejuvenation that repairs skin at a deeper level rather than just hydrating the surface.

Before & Afters

Subtle refinement achieved through precision, proportion, and restraint. At Dr Hass Clinic, no two results are ever the same.

cosmetic trends

Benefits of Polynucleotide Injections

Polynucleotide injections provide a range of benefits, including:

  • Skin Rejuvenation: Improves skin texture, firmness, and hydration levels.
  • Anti-Ageing: Reduces fine lines and wrinkles by boosting collagen and elastin production.
  • Skin Repair: Accelerates healing and regeneration, particularly after skin damage or aesthetic treatments.
  • Natural Results: Enhances your natural beauty without altering facial expressions.
  • Safe and Biocompatible: Well-tolerated and suitable for most skin types.

Your Polynucleotide Journey: Step by Step

Your polynucleotide treatment at Dr Hass Clinic follows a precise, personalised process designed for optimal results and comfort:

1. Consultation:
Step 1 of 5

1. Consultation:

Your journey starts with a detailed assessment by Dr Hasaneen Al Janabi, who evaluates your skin condition and discusses your aesthetic goals to create a tailored treatment plan.

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2. Preparation and Treatment:
Step 2 of 5

2. Preparation and Treatment:

On the day, targeted areas are cleansed, and numbing is applied if needed. Dr Hasaneen then administers the polynucleotide injections with precision to encourage natural skin renewal and rejuvenation.

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3. Recovery:
Step 3 of 5

3. Recovery:

Mild redness or swelling may appear but usually resolves within a few days, with minimal downtime.

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4. Aftercare Guidance:
Step 4 of 5

4. Aftercare Guidance:

You will receive clear instructions to support healing and maximise results, ensuring your skin remains healthy and radiant.

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5. Follow-Up:
Step 5 of 5

5. Follow-Up:

To maintain long-lasting benefits, follow-up treatments are typically recommended every 6 to 9 months.

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Contact Us

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Dr Hass Clinic

Accreditations & Professional Memberships

Polynucleotides for Under-Eye Rejuvenation

The under-eye area is thin and delicate, making it one of the first places to show fine lines, crepiness, and hollowing. Polynucleotides work differently to traditional fillers here:

  • They regenerate rather than volumise. Tear trough filler adds volume to smooth hollowing, while polynucleotides stimulate collagen and elastin to improve the skin itself.
  • They hydrate thin skin, improving elasticity and softening crepey texture.
  • They soften dark circles by supporting microcirculation, without adding bulk to the area.
  • They can be combined with tear trough filler for patients dealing with both hollowing and poor skin quality.

Read more about polynucleotides for under-eye rejuvenation →

Dermal filler at Dr Hass Clinic

Why Choose Dr Hass Clinic?

Trust your results to expert medical care at Dr Hass Clinic, where every treatment combines clinical precision with aesthetic artistry for natural, refined outcomes.

  • All procedures are performed by Dr Hasaneen Al Janabi, a GMC-registered aesthetics doctor and Royal College of Surgeons member, who has treated over 10,000 patients with exceptional results.
  • Each treatment is 100% personalised to your skin’s unique needs, using premium, clinically proven products for lasting, natural rejuvenation.
  • You will receive comprehensive care from consultation to aftercare and follow-up, ensuring optimal safety, comfort, and confidence.
  • Our Mayfair clinic provides a luxurious, discreet setting designed for your comfort and peace of mind.
Dr Hasaneen Al Janabi - Dr Hass Clinic

FAQs

How do polynucleotide injections improve skin elasticity?

Polynucleotides stimulate fibroblasts, the cells responsible for producing collagen and elastin. These are key proteins that maintain skin’s firmness and elasticity. This boost helps tighten and strengthen the skin, reducing sagging and giving a more lifted, youthful appearance.

What areas can be treated with polynucleotides?

Common treatment areas include the under-eyes, cheeks, neck, décolletage, hands, arms, and even the scalp for improving hair and skin health.

Are polynucleotide injections safe?

Yes, they are highly biocompatible and safe for most individuals. Our team at Dr Hass Clinic ensures the highest standards of safety and care during every treatment.

Are polynucleotide injections suitable for sensitive skin?

Yes, they are highly biocompatible and safe for most individuals. Our team at Dr Hass Clinic ensures the highest standards of safety and care during every treatment.

How many treatments are usually needed?

Typically, an initial course of 1 to 3 sessions is recommended, spaced about 2 to 4 weeks apart. Maintenance sessions are encouraged every 8 to 12 months.

How soon will I see results?

Results typically become noticeable within 1-2 weeks after treatment, as the skin begins to repair and rejuvenate itself. Improvements will continue over the following weeks as collagen production increases.

How long do the results last?

The effects can last up to six months or more, depending on your skin type, lifestyle, and the number of sessions completed. Periodic maintenance treatments are recommended for optimal, long-lasting results.

Is the treatment painful?

The injections are generally well-tolerated by patients. A topical numbing cream can be applied before the procedure to minimise any discomfort during the treatment.

Is there downtime after polynucleotide treatment?

Most patients resume normal activities immediately after treatment. Minor redness or swelling may occur but typically resolves within a few days.

What should I avoid after the treatment?

After your treatment, it is recommended to avoid intense exercise, saunas, and direct sun exposure for at least 24-48 hours to ensure optimal results and reduce the risk of irritation.

How do polynucleotide injections differ from other skin rejuvenation treatments?

Unlike hyaluronic acid-based fillers, which primarily add volume, polynucleotide injections focus on repairing and regenerating the skin at a cellular level. They provide long-lasting improvements in skin quality, hydration, and elasticity rather than temporary volumising effects.

Dr Hass Clinic Frequently Asked Questions
Dr Hass Clinic Frequently Asked Questions

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Maya Ansar
4 days ago
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A very good experience. Dr Hass was professional, thorough and took the time to assess my face properly. The face mapping was very detailed, everything was explained clearly, and the recommendations felt considered rather than rushed. I felt very comfortable throughout.
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Lekaa Saleh
6 days ago
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I am a lady in my early 50s I was very confused to choose a clinic that can remove my double chin which was really annoying me and making me lose my confidence. I finally found Dr. Hass clinic. I am a person who doesn’t like surgeries or injections.. I was very worried but Dr Hass was a very experienced professional doctor who made me feel comfortable and relaxed. I personally didn’t feel any pain and when I saw the result I was amazed with the beautiful change … No more double chin 🥹🥹 It’s very important for all women to invest in their health and beauty.. I strongly recommend Dr Hass clinic and I would love to make another visit for different treatments 😊 Dr Hass you really changed my life by increasing my self confidence thank you so so much for everything 🥹🙏🏼🌹
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Ambar Mirza
10 days ago
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I’ve been coming to Dr Hass for a long time now and I honestly wouldn’t trust anyone else with my filler. He always makes me feel completely at ease and really takes the time to listen to what I want, while also giving genuinely helpful and honest advice. He’s brilliant at what he does, couldn’t recommend him enough!
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jenai douglas
11 days ago
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I visited Dr Hass for dermal fillers and it was my best experience to date. Dr Hass took time during the consultation to really ask questions to understand my needs and make the best recommendations for me to achieve my desired results. He was honest and personable and even advised me against treatments I thought I needed due to seeing others have these procedures online. He really cared about my results and being satisfied over anything else. I was nervous but he put me at ease and the results are amazing. Cannot recommend the clinic enough and I will be back!
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Nikol
12 days ago
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Endolift A huge thank you to Dr. Haas! I had a big issue with sagging skin, especially on my neck, so I decided to get an Endolift for my face with an extended neck treatment. I saw the results immediately after the procedure—my skin was tightened, my facial contours were much more defined, and everything looked so beautiful and natural. I am extremely satisfied, the clinic is clean and gorgeous, and everyone there is so kind. Dr. Haas is truly one of the best doctors, and I highly recommend him to everyone!
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lola ri
12 days ago
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Dr Hass is truly magical! He has an incredible eye and knows exactly what your face needs to create the perfect contour while keeping everything natural and beautifully balanced. His skill and attention to detail are exceptional I couldn’t be happier with the result. I highly recommend him!
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Nikol Rosenbergova
12 days ago
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I recently went to Dr. Hass at Dr. Hass Clinic for an Endolift treatment, and I honestly couldn't be happier with the results! I had quite a bit of sagging skin, especially around my neck and lower face. The moment the procedure was done, I could immediately feel the tightening effect. The results were amazing right away the sagging on my neck completely disappeared, and my facial contours were lifted instantly. Dr. Hass is wonderful, so kind, and extremely professional. He explained everything in detail and took his time to focus precisely on the sagging areas where I needed it the most. I am so satisfied with my experience, I will definitely come back in the future, and I highly recommend him to anyone struggling with similar issues. He is truly one of the best, and I am so glad I found him and chose him!
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Caroline Wingfield
19 days ago
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Lips I would thoroughly recommend Dr Hass and his clinic. He is incredibly thorough, professional and, most importantly, honest in his approach. Having visited a number of different clinics over the years, what really sets Dr Hass apart is his focus on achieving a softer, fresher and more natural look rather than making you look “done”. He has completely transformed years of previous lip filler for me, and my lips already look amazing — beautifully natural and so much better balanced. I’ve had so many people notice the difference and comment on how good they look. I couldn’t be happier with the results and wouldn’t hesitate to recommend him.
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Rume Rahman
23 days ago
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I spent years looking for an effective treatment for my jawline and came across Dr Hass's clinic on instagram. I am extremely happy with the results of endolift and a mini liposuction. The service was exceptional from beginning to the after care. Dr Hass always responds to queries and gives appropriate advice. I would highly recommend his services.
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Lucy Bridgeman
55 days ago
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Would highly recommend the Dr Hass Clinic. From booking my initial consultation right through to aftercare, every interaction has been quick, easy and professional. After having Endolift on my face with exceptional results, I had no hesitation in booking an Endolift body treatment for my thighs. Due to the amount of loose skin, I had always assumed surgery was my only option. I didn’t want to trade sagging skin for scars, and I also didn’t have the budget or the time for surgery and a lengthy recovery. I was therefore over the moon when Dr Hass explained that I could achieve visible skin tightening results with Endolift. I’ve just had the treatment, so I’m now really excited to see the results develop! The level of care, expertise and attention throughout has been brilliant. I’m particularly self-conscious about my thighs, but Dr Hass made me feel completely at ease and comfortable throughout the consultation and treatment. The treatment itself was also practically pain-free. I genuinely wouldn’t hesitate to recommend Dr Hass and his clinic. He clearly knows his stuff, takes great care of his patients and, as an added bonus, is actually a really cool guy to spend a few hours, I’m now a country music fan too!
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Monika Lescevska
60 days ago
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I am so lucky to have found Dr. Hass. I recently did an Endolift procedure on my body and couldn't be happier that I chose to go with this clinic. I first had a consultation where Dr. Hass went through the whole procedure in detail and made me feel heard. I then came in for the actual procedure, feeling quite anxious as I never had anything similar done. The procedure went through so smoothly, and the pain was very minimal. Dr. Hass ensured I felt comfortable, and was very patient with me the entire time. He is definitely at the top of his field, so I felt safe being in his hands. I'm still in the process of recovery but I have minimal bruising and swelling and everything is healing really well. I already told Dr. Hass that I will come to him for any future procedure or cosmetic enhancement!
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Lisa
64 days ago
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Dr Hass performed an Endolift procedure on my sub mental area.My experience exceeded my expectations. Dr Hass reassured me all the way through the procedure and I had zero pain.I am excited to see my results.If you are considering this treatment with Dr Hass I would not hesitate to go ahead.
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Amy Barker
65 days ago
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Great experience from Dr Hass, really pleased with the results of my under eye endolift
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Charlotte Mackinnon
66 days ago
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I visited Dr. Hass for a non-surgical nose treatment and I couldn't be happier with the results. My nose was lifted instantly and the whole procedure was very quick and painless. I don't live in the UK, but I would absolutely travel back to London to have this treatment done again. I highly recommend Dr. Hass
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Anju
71 days ago
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Dr Hass is incredibly helpful and truly an expert in his field. He explains everything thoroughly and clearly, which made me feel completely at ease throughout my treatment. I felt in very safe hands from start to finish. Thank you!

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