Published by Dr Hasaneen
Published date 21.11.25
The field of medical aesthetics continues to advance, offering increasingly refined ways to rejuvenate the skin and restore a youthful appearance. Among the most talked-about treatments at the moment are polynucleotides and dermal fillers.
While both can help revitalise the face, they work in very different ways. Understanding how each treatment functions will help you make an informed decision about which one best aligns with your aesthetic goals.
If you are looking to enhance your skin or facial structure but feel unsure where to begin, you are not alone.
At Dr Hass Clinic, we believe every patient should have clear, accurate information before choosing a treatment. Whether you are new to injectables or simply exploring new options, our team is here to guide you through the process with honesty and expertise.
Polynucleotides are a new generation of regenerative injectables that focus on improving skin quality rather than altering facial shape.
They are made from purified DNA fragments, most commonly derived from salmon or trout, which have remarkable bio-stimulating properties. When injected into the skin, polynucleotides encourage the body’s natural healing processes by:
This treatment works at a cellular level to strengthen and revitalise the skin from within.
Polynucleotides are especially beneficial for:
Results develop gradually over several weeks, creating a refreshed and healthier complexion that looks natural and well-rested.
Dermal fillers are injectable gels, most often made from hyaluronic acid (HA), a substance that naturally occurs in the skin. Their purpose is to restore lost volume, refine contours and smooth deeper lines.
Unlike polynucleotides, which work by regenerating skin tissue, dermal fillers physically add volume beneath the skin to lift and sculpt specific areas.
They are commonly used for:
Results from dermal fillers are visible immediately and typically last between 6 and 18 months, depending on the product used and the area treated.
Here are some additional benefits of dermal fillers, outlined by specific areas of the face:
Both treatments rejuvenate the face, but their mechanisms and results are quite distinct.
The right choice depends on what you hope to achieve.
If your goal is to improve skin quality, boost hydration and achieve a naturally radiant look, polynucleotides are an excellent option. They support your skin’s biology, helping it to repair and regenerate from within.
If you wish to restore lost volume or enhance your facial contours, dermal fillers are more suitable. They provide structure, lift and definition with immediate results.
In many cases, a combination of both treatments can be particularly effective. Polynucleotides improve skin tone and texture, while fillers restore balance and youthful contours.
At Dr Hass Clinic, we take pride in providing a safe, patient-focused experience from consultation to aftercare.
Still unsure? We have you covered.
Can I combine both treatments?
Yes. Many patients benefit from combining polynucleotides with dermal fillers for a more complete rejuvenation effect.
Are polynucleotides better than fillers?
They are not better or worse, simply different. Polynucleotides enhance the skin itself, while fillers restore shape and structure.
When will I see results?
Dermal filler results are immediate. Polynucleotides work more gradually, with visible improvement over several weeks.
Will the results look natural?
Absolutely. At Dr Hass Clinic, we specialise in subtle enhancements that complement your natural beauty without altering your individuality.
Both polynucleotides and dermal fillers are powerful tools in modern aesthetic medicine. Polynucleotides focus on skin regeneration and repair, while dermal fillers restore structure and volume for a more lifted appearance.
At Dr Hass Clinic, our philosophy is centred on achieving elegant, natural results tailored to each individual. Whether you wish to revitalise your skin or enhance your facial contours, our team will guide you towards the most appropriate treatment for your goals.
Book your consultation today to discover how these advanced treatments can work together to help you look and feel your best.
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